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Download Complete Issue (PDF 2.1MB)

Guest Editorial

Bridging the Gap: The International Federation of Biosafety Associations(PDF 76KB)
J. Craig Reed

Letters to the Editors

Challenges to Defining Biosecurity and Accurately Capturing Biosecurity Costs(PDF 64KB)
Kirk R. Wilhelm

Articles

Evaluation of the Effects of Radiation from an X-ray Baggage Inspection System on Microbial Agents(PDF 848KB)
Jay Krishnan, Bradley Cook, Tim Schrader, and Steven Theriault

Stem Cell Technology—Emerging Framework for Hazard Assessment and Biosafety Considerations(PDF 192KB)
Venkat Rao

Inactivation of Brucella suis, Burkholderia pseudomallei, Francisella tularensis, and Yersinia pestis Using Vaporous Hydrogen Peroxide(PDF 114KB)
James V. Rogers, William R. Richter, Morgan Q. S. Wendling, and Adrienne M. Shesky

Contained Use of Bacteriophages: Risk Assessment and Biosafety Recommendations (PDF 184KB)
Céline Verheust, Katia Pauwels, Jacques Mahillon, Donald R. Helinski, and Philippe Herman

Special Features

Ask the Experts—Can We Go Too Far with Implementing Safety Practices?(PDF 48KB)
John H. Keene

 

About the Cover

Stem cell research provides a useful tool for unraveling the molecular mechanisms that determine the differentiation fate of a pluripotent cell and for understanding the gene expression properties and epigenetic modifications essential to maintain the pluripotent state. In the future, this knowledge may be used to generate cells for transplantation therapies, whereby a specific cell population compromised by disease is replaced with new, functional cells. Differentiated derivatives of human pluripotent cells may also prove to be useful as models for understanding the biology of disease and developing new drugs, particularly when there is no animal model for the disease being studied. The greatest promise of stem cell research may lie in an area not yet imagined.

Image and description from Stem Cell Information (World Wide Web site). Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2009 (cited Friday, February 5, 2010). Available at: http://stemcells.nih.gov/info/media/promise. ©2008 Terese Winslow. For biosafety information on stem cells, see "Stem Cell Technology—Emerging Framework for Hazard Assessment and Biosafety Considerations" by Venkat Rao on pages 15-24.