Biosafety Links
Pertinent Government Agency Alerts
Rumor Management
Urban Myths
http://www.urbanmyths.com/
CDC Rumors and Hoaxes
http://www.cdc.gov/hoax_rumors.htm
Agencies
Department of Health and Human Services
Center for Disease Control and Prevention
NIH Office of Biotechnology Activities (OBA)
Food and Drug Administration (FDA)
National Institute for Occupational Safety and Health (NIOSH)
Department of Agriculture (USDA)
Animal Plant Health Inspection Service (APHIS)
U.S. Department of Transportation (DOT)
US Environmental Protection Agency (EPA)
General Regulatory Agency Links
OSHA Home Page
http://www.osha.gov/
Environmental Protection Agency Home Page
http://www.epa.gov/
Nuclear Regulatory Commission Home Page
http://www.nrc.gov/
Food and Drug Administration Home Page
http://www.fda.gov/
Research and Special Projects Administration (RSPA)
http://www.rita.dot.gov/
Federal Register Search Engine
http://www.gpoaccess.gov/fr/search.html
Code of Federal Regulations Search Engine
http://www.gpoaccess.gov/cfr/index.html
ABSA/OSHA Fact Sheets
General Microbiology Fact Sheet(PDF 3.5MB)
Select Agent Disease Fact Sheet(PDF 368KB)
Zoonotic Fact Sheet(PDF 480KB)
Principles of Good Microbiological Practice Fact Sheet(PDF 135KB)
Principles of Biosafety Fact Sheet (PDF 56KB)
For best results print fact sheets on
legal-sized paper with a color printer.
Government and Other Technical Agencies
These are agencies with references to EHS in general and biological safety in particular.
WHO Home Page
http://www.who.int/
Belgian Biosafety Server (This site has tons of references for all of Europe!)
http://www.biosafety.be/
Health and Safety Executive UK
http://www.hse.gov.uk/hsehome.htm
NIOSH Home Page
http://www.cdc.gov/niosh/homepage.html
ORDA Home Page
http://www4.od.nih.gov/oba/
NIH rDNA Guidelines (new format)
http://oba.od.nih.gov/rdna/nih_guidelines_oba.html
CDC Home Page
http://www.cdc.gov/
International Air Transport Association
http://www.iata.org/whatwedo/cargo/dangerous_goods/Pages/index.aspx
National Sanitation Foundation Internal Home Page
http://www.nsf.org/
State Government Web Sites
50 State's Workman's Compensation Web Sites
http://www.ic.nc.gov/ncic/pages/all50.htm
50 State's Regulatory Agencies Web Sites
http://www.clay.net/statag.html
State and Local Government on the Net
http://www.statelocalgov.net
International
CEN Laboratory Biorisk Management Standard
Belgian Biosafety Server (European Biosafety Topics)
Office of Biosafety, LCDC (Canada)
OHASIS, Office of Health and Safety Information Systems (CDC)
International Veterinary Biosafety Workgroup
European Biosafety Association
Biosafety Guidelines
Guidelines for Safe Work Practices in Human and Animal Medical Diagnostic Laboratories, Recommendations of a CDC-convened, Biosafety Blue Ribbon Panel, CDC, Morbidity and Mortality Weekly Report (MMWR), January 6, 2012
Guidelines for Biosafety Laboratory Competency(PDF 420KB), CDC/APHL, Morbidity and Mortality Weekly Report, April 15, 2011
CDC/NIH: Biosafety in Microbiological and Biomedical Laboratories
5th Edition, 2007.
International Biosafety Working Group (IBWG)
S3: Science, Safety, and Security
Biosecurity, Biosafety, Biocontainment, and Biorisk management
CDC/NIH: Primary Containment for Biohazards: Selection, Installation and
Use of Biological Safety Cabinets(PDF )
3rd edition, September 2007
CETA Application Guide for the Exhaust System Requirements of Class II, Type B Biosafety Cabinets(PDF )
CAG-007-2010, March 24, 2010
Guidelines for the Safe Transport of Infectious Substances and Diagnostic Specimens (PDF 288k)
WHO-1997
LCDC, Canada: Laboratory Biosafety Guidelines (PDF)
3rd Edition, 2004.
NIH Design Criteria for laboratory construction
World Health Organization Laboratory Biosafety Manual
3rd Edition, 2004.
Rules / Regulations / Guidelines
Swine Influenza A (H1N1) Virus Biosafety Guidelines for Laboratory Workers
HHS security guidelines for synthetic DNA manufacturers
Bloodborne Pathogens
29 CFR 1910.1030 (OSHA)
Bloodborne Pathogens Compliance Directive (PDF)
Hazardous Materials Regulations (49 CFR 100-185)
Select Agent Final Rule
Department of Health and Human Services (DHHS) (PDF 247KB)
CDC Correspondence to ABSA
regarding Final Rule(MSWord 48k)
Select Agent Final Rule
US Department of Agriculture (USDA) (PDF 333KB)
Hazardous Waste (EPA)
NIH Guidelines for Research Involving Recombinant DNA Molecules
Microbiology (EPA)
IAQ (EPA)
Needlestick Standard (OSHA)
Respirator (NIOSH)
Occupational Exposure to Hazardous Chemicals in Laboratories
29 CFR 1910.1450 (OSHA)
Pocket Guide to Chemical Hazards
Personal Protective Equipment
(29 CFR 1910.132-139)
Food and Drug Administration (FDA)
Animal Plant Health Inspection Service (APHIS)
WHO Laboratory Biosecurity Guidance
Material Safety Data Sheets for Infectious Agents (Health Canada)
Import and Export Permits for Pathogens and Infectious Agents
CDC import permit applications are available from the following site:
http://www.cdc.gov/od/ohs/biosfty/imprtper.htm
US Department of Commerce provides information on the export of infectious substances and other biological materials:
http://www.bxa.doc.gov/
Both the BMBL and Etiologic Agent permits pages and other biosafety reference information can be reached through the CDC Office of Health and Safety biosafety page:
http://www.cdc.gov/od/ohs/biosfty/biosfty.htm
USDA Veterinary Services National Center for Import and Export
http://www.aphis.usda.gov/NCIE/
APHIS web site for import and shipment permits for animal and plant pathogens as well as biotechnology (plant and agricultural microorganism) permits:
http://www.aphis.usda.gov/import.html
Draft FDA guidance document on selection of disposable gloves
http://www.fda.gov/cdrh/comp/guidance/1141.pdf
AIHA Biosafety web link
http://www.aiha.org/insideaiha/volunteergroups/labHandScommittee/LabHSTechnicalTopics/Pages/Biosafety.aspx
NIH Division of Safety Publications web site
http://www.nih.gov/od/ors/ds/pubs/index.html
Dictionary of Safety Terms - Spanish to English
http://www.orosha.org/pdf/dictionary/spanish-english.pdf
Dictionary of Safety Terms - English to Spanish
http://www.orosha.org/pdf/dictionary/english-spanish.pdf
BMBL Change Matrix
Download the ABSL1-4 Matrix(XLS 312KB)
Download the BSL2-4 Matrix(XLS 300KB)
UPDATED--Letter to the Editors as published in (Vol. 13, No. 3, 2008)
Infectious Substances Shipping Guidelines
Everything you need to know about shipping infectious substances safely. Learn how to ship infectious substances by any mode of transport anywhere in the world. The Infectious Substances Shipping Guidelines are outlined in a convenient, easy-to-read manual with up-to-date information on the regulations. This time saving handbook features easy-to-follow transportation guidelines for road, air and courier, sets out national and international regulations and provides training requirements and examples of actual documentation. The how-to checklists cover every step of the shipping process including classification, identification, packaging, marking, labelling and handling. Published annually only in English.
Link for IATA online store: https://www.iataonline.com/Store/default.htm
Biosecurity
ABSA Biosecurity Task Force White Paper: Understanding Biosecurity (January 2003)
FAQs for New Select Agent Regulation (42 CFR 73)
Interim Final Rule: CDC; Possession, Use, and Transfer of Select Agents and Toxins; 42 CFR Part 73
USA PATRIOT Act: Expansion of the Biological Weapons Statute (PDF 64k)
Bioterrorism
AAAS Center for Science, Technology and Security Policy
http://cstsp.aaas.org
Bioterorism Resources, Association for Professionals in Infection Control and Epidemiology, Inc.
http://www.apic.org/Content/NavigationMenu/PracticeGuidance/Topics/Bioterrorism/Bioterrorism.htm
CDC's Bioterrrorism web site
http://www.bt.cdc.gov/
U.S.Army Medical Research Institute of Infectious Diseases (USARMRIID), Fort Detrick, MD
http://www.usamriid.army.mil/
Health Canada/ Office of Biosafety : Bioterrorism Statement
http://www.hc-sc.gc.ca/pphb-dgspsp/publicat/ccdr-rmtc/01vol27/dr2704ea.html
Bioterrorism Readiness Plan - A Template for Health Care Facilities, APIC
http://www.apic.org/Content/NavigationMenu/PracticeGuidance/Topics/Bioterrorism/Bioterrorism.htm#Readiness_Planning
Bioterrorism and Public Health Summary (Health Canada)
http://www.hc-sc.gc.ca/pphb-dgspsp/publicat/ccdr-rmtc/01vol27/dr2704ea.html
Biological and Chemical Terrorism: Strategic Plan for Preparedness and Response. Recommendations of the CDC Strategic Planning Workgroup. MMWR 49 (RR04):1-14. April 21,2000
http://www.cdc.gov/mmwr/preview/mmwrhtml/rr4904a1.htm
Chemical and Biological Arms Control Report - Bioterrorism in the United States : The Threat, Preparedness and Response
http://www.cbaci.org/
Center for the Study of Bioterrorism and Emerging Infections (St. Louis University)
http://bioterrorism.slu.edu/
Center for Biodefense Studies (John Hopkins University)
http://www.hopkins-biodefense.org/
Hawley, Robert J., PhD. "Biological Weapons - A Primer for Microbiologists", Annual Review of Microbiology and Human Genetics, 55:235-253. 2001.
http://micro.annualreviews.org/cgi/content/full/55/1/235?ijkey=enEHjLfv2n34o&keytype=ref
Chemical, Biological, Radiological & Nuclear Defense Information Analysis Center
https://www.cbrniac.apgea.army.mil
FM3-3 Chemical and Biological Contamination Avoidance, Chapter 4, Biological Agents, U. S. Army
http://library.enlisted.info/field-manuals/series-3/FM3-3/CH4.PDF
Chemical and Biological Weapons Non-proliferation Project
http://cns.miis.edu/programs/cbwnp/
Federation of American Scientists, Non Proliferation of Weapons of Mass Destruction
http://www.fas.org/
Title 32 CFR 627, Subpart H.200, DA Pamphlet 385-69. The Biological Defense Program. Technical Safety Requirements
http://www.access.gpo.gov/nara/cfr/waisidx_00/32cfr627_00.html
Medscape - Bioterrorism: Preparing for the Future (Accessible from CDC Bioterrorism web site, you must register to access information through Medscape)
http://www.medscape.com/
National Symposium on Medical and Public Health Response to Bioterrrorism, Emerging Infectious Diseases, Volume 5, No. 4, July - August 1999
http://www.cdc.gov/ncidod/eid/vol5no4/pdf/v5n4.pdf
NATO Handbook on the Medical Aspects of Defensive Operations AmedP-6(B), Part II -Biological
http://www.fas.org/nuke/guide/usa/doctrine/dod/fm8-9/2toc.htm
Investigating Disease Outbreaks under a Protocol to the Biological and Toxin Weapons Convention
Mark Wheelis, University of California, Davis, California USA . Emerging Infectious Diseases 6 (6) 2000 CDC
http://www.cdc.gov/ncidod/eid/vol6no6/wheelis.htm
State Bioterrorism Bills/Laws/Regulations
North Carolina Bioterrorism Agent Registry
http://www.epi.state.nc.us/epi/bioagent/
Technical Links & Papers
NIH Genetic Modification Clinical Research Information System (GeMCRIS)
http://www.gemcris.od.nih.gov/
American Conference of Governmental Industrial Hygienists (ACGIH)
http://www.acgih.org
American Industrial Hygiene Association (AIHA)
http://www.aiha.org
From the CDC web site: CDC Hospital Infection Programs http://www.cdc.gov/ncidod/hip/
January 17, 1997 CDC Needle Safety Device Study
http://www.cdc.gov/mmwr/preview/mmwrhtml/00045648.htm
RTECS - Registry of Toxic Effects of Chemical Substances
http://www.cdc.gov/niosh/rtecs.html
The BMBL is available directly from:
http://www.cdc.gov/od/ohs/biosfty/bmbl5/bmbl5toc.htm
CDC Prevention Guidelines Database
http://aepo-xdv-www.epo.cdc.gov/wonder/PrevGuid/PrevGuid.htm
Consolidated CDC Post- Exposure Recommendations (June 29,2001)
http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5011a1.htm
DHHS/PHS National Toxicology Program, 10th Report on Carcinogens
http://ntp.niehs.nih.gov/index.cfm?objectid=72016262-BDB7-CEBA-FA60E922B18C2540
From the OSHA web site:
Latex Allergy folder
http://www.osha.gov/SLTC/latexallergy/index.html
Needlestick Prevention Folder, including the revised OSHA bloodborne pathogen compliance directive
http://www.osha.gov/SLTC/needlestick/index.html
The above OSHA needlestick folder includes links to the following sites:
University of Virginia Health Care Worker Safety Center
http://www.healthsystem.virginia.edu/internet/epinet/
Emergency Care Research Institute
http://www.ecri.org/
Training for Development of Innovative Control Technologies
http://www.tdict.org/
California SHARPS Program
http://www.dir.ca.gov/dosh/cal_vpp/eagle.html
More technical web links
Occupational & Environmental Medicine
http://www.acoem.org/welcome.htm
National Pesticide Information Center
http://npic.orst.edu/
Canadian Pathogen Safety Data Sheets (PSDS)
http://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/index-eng.php
American Type Culture Collection
http://www.atcc.org/
Virus Databases on Line
http://www.ictvdb.org/
Journal of Gene Medicine
http://onlinelibrary.wiley.com/journal/10.1002/%28ISSN%291521-2254
Knowing How to Practice Safe Science (Howard Hughes Institute)
http://www.practicingsafescience.org/
OIE - World Organization for Animal Health
http://www.oie.int/eng/en_index.htm
More CDC articles
Update: Investigation of Anthrax Associated with Intentional Exposure and Interim Public Health Guidelines, October, 2001
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5041a1.htm
Recognition of Illness Associated with the Intentional Release of a Biologic Agent
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5041a2.htm
Investigation of case of anthrax in Texas Laboratory Worker
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5113a4.htm
Investigation of case of anthrax in Texas Laboratory Worker
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5122a4.htm
State of Alaska Department of Human Services : Bugwars (Community Tabletop Bioterrorism Exercise)
http://www.ci.anchorage.ak.us/healthchd/bugwars.cfm
ASHRAE Report: "Risk Management Guidance for Health and Safety Under Extraordinary Circumstances" - January 12, 2002 (PDF. file, under "News and Events")
http://www.ashrae.org/
Lawrence Berkley National Laboratory
http://securebuildings.lbl.gov/
CDC/NIH: Guidance for Protecting Building Environments from Airborne Chemical, Biological and Radiological Attacks
http://www.cdc.gov/niosh/bldvent/2002-139.html
Office of Homeland Security
http://www.whitehouse.gov/homeland/
You may need to download Acrobat Reader