Biosafety Links


General Regulatory Agency Links
Government and Other Technical Agencies
State Government Web Sites
Pertinent Government Agency Alerts
Rumor Management
ABSA/OSHA Fact Sheets


Import and Export Permits for
Pathogens and Infectious Agents

Biosafety Guidelines
BMBL Change Matrix
Infectious Shipping


State Bioterrorism Bills/Laws/Regulations

Technical Links & Papers

More technical web links
More CDC articles

Also, See Training Tools/Resources


Pertinent Government Agency Alerts

NIOSH Needlestick Alert

NIOSH Latex Safety Alert

NIOSH Animal Asthma Alert


Rumor Management

Urban Myths

CDC Rumors and Hoaxes



Department of Health and Human Services

Center for Disease Control and Prevention

NIH Office of Biotechnology Activities (OBA)

Food and Drug Administration (FDA)

National Institute for Occupational Safety and Health (NIOSH)

Department of Agriculture (USDA)

Animal Plant Health Inspection Service (APHIS)

U.S. Department of Transportation (DOT)

US Environmental Protection Agency (EPA)


General Regulatory Agency Links

OSHA Home Page

Environmental Protection Agency Home Page

Nuclear Regulatory Commission Home Page

Food and Drug Administration Home Page

Research and Special Projects Administration (RSPA)

Federal Register Search Engine

Code of Federal Regulations Search Engine


Government and Other Technical Agencies

These are agencies with references to EHS in general and biological safety in particular.

WHO Home Page

Belgian Biosafety Server (This site has tons of references for all of Europe!)

Health and Safety Executive UK

NIOSH Home Page

ORDA Home Page

NIH rDNA Guidelines (new format)

CDC Home Page

International Air Transport Association

National Sanitation Foundation Internal Home Page


State Government Web Sites

State Workers' Compensation Officials

50 State's Regulatory Agencies Web Sites

State and Local Government on the Net



CEN Laboratory Biorisk Management Standard

Belgian Biosafety Server (European Biosafety Topics)

Office of Biosafety, LCDC (Canada)

OHASIS, Office of Health and Safety Information Systems (CDC)

Select Agent Website

International Veterinary Biosafety Workgroup

European Biosafety Association


Rules / Regulations / Guidelines


Animal Plant Health Inspection Service (APHIS)

ANSI/ASSE Z9.14-2014 Standard

Bloodborne Pathogens
29 CFR 1910.1030 (OSHA)

Bloodborne Pathogens Compliance Directive (PDF)

CDC Correspondence to ABSA
regarding Final Rule
(MSWord 48k)

United States Government Policy for Institutional Oversight of Life Sciences Dual Use Research of Concern
Released September 24, 2014
DURC Policy(PDF 616KB)
DURC Companion Guide(PDF 901KB)

Food and Drug Administration (FDA)

Hazardous Materials Regulations (49 CFR 100-185)

HazMat Safety

Hazardous Waste (EPA)

HHS security guidelines for synthetic DNA manufacturers


IBC Resources

Microbiology (EPA)

NAPPO APPROVED RSPM 22 "Guidelines for Construction and Operation of a Containment Facilityfor Insect and Mite Biological Control Agents"

Needlestick Standard (OSHA)

NIH Guidelines for Research Involving Recombinant DNA Molecules

Occupational Exposure to Hazardous Chemicals in Laboratories
29 CFR 1910.1450 (OSHA)

Pathogen Safety Data Sheets and Risk Assessment(Public Health Agency of Canada)

Pocket Guide to Chemical Hazards

Personal Protective Equipment
(29 CFR 1910.132-139)

Respirator (NIOSH)

Select Agent Final Rule
Department of Health and Human Services (DHHS)
(PDF 247KB)

Select Agent Final Rule
US Department of Agriculture (USDA) (PDF 333KB)

Swine Influenza A (H1N1) Virus Biosafety Guidelines for Laboratory Workers

WHO Laboratory Biosecurity Guidance


Import and Export Permits for Pathogens and Infectious Agents

CDC import permit applications are available from the following site:

US Department of Commerce provides information on the export of infectious substances and other biological materials:
[link broken make a suggestion]

Both the BMBL and Etiologic Agent permits pages and other biosafety reference information can be reached through the CDC Office of Health and Safety biosafety page:

USDA Veterinary Services National Center for Import and Export
[link broken make a suggestion]

APHIS web site for import and shipment permits for animal and plant pathogens as well as biotechnology (plant and agricultural microorganism) permits:

Draft FDA guidance document on selection of disposable gloves

AIHA Biosafety web link

NIH Division of Safety Publications web site

Dictionary of Safety Terms - Spanish to English

Dictionary of Safety Terms - English to Spanish


BMBL Change Matrix

Applied Biosafety Journal Article - Comparative Analysis of the Fourth and Fifth Editions of Biosafety in Microbiological and Biomedical Laboratories, Vertebrate Animal Biosafety Level Criteria (ABSL1-4)(PDF 116KB)

Download the ABSL1-4 Matrix(XLS 312KB)

Applied Biosafety Journal Article - Comparative Analysis of the Fourth and Fifth Editions of Biosafety in Microbiological and Biomedical Laboratories Section IV (BSL2-4)(PDF 176KB)

Download the BSL2-4 Matrix(XLS 300KB)

UPDATED--Letter to the Editors as published in (Vol. 13, No. 3, 2008)


Infectious Substances Shipping Guidelines

Everything you need to know about shipping infectious substances safely. Learn how to ship infectious substances by any mode of transport anywhere in the world. The Infectious Substances Shipping Guidelines are outlined in a convenient, easy-to-read manual with up-to-date information on the regulations. This time saving handbook features easy-to-follow transportation guidelines for road, air and courier, sets out national and international regulations and provides training requirements and examples of actual documentation. The how-to checklists cover every step of the shipping process including classification, identification, packaging, marking, labelling and handling. Published annually only in English.

Link for IATA online store:



ABSA Biosecurity Task Force White Paper: Understanding Biosecurity (January 2003)

Security Considerations for Microbiological and Biomedical Facilities, Anthology of Biosafety V - BSL4 Laboratories, Chapter 6 (2002)

Understanding, Assessing, and Communicating Topics Related to Risk in Biomedical Research Facilities, Anthology of Biosafety IV - Issues in Public Health, Chapter 10 (2001)

FAQs for New Select Agent Regulation (42 CFR 73)

Interim Final Rule: CDC; Possession, Use, and Transfer of Select Agents and Toxins; 42 CFR Part 73

Interim Rule: Animal and Plant Health Inspection Service; Agricultural Bioterrorism Protection Act of 2002; Possession, Use, and Transfer of Biological Agents and Toxins [link broken make a suggestion]

Laboratory Security and Emergency Response Guidance for Laboratories Working with Select Agents -MMWR 51(RR19)

USA PATRIOT Act: Expansion of the Biological Weapons Statute (PDF 64k)

"Does Your Research Have Dual Use Potential?". Brochure available in PDF form on the Web site of the NIH Office of Biotechnology Activities (PDF 420k)



AAAS Center for Science, Technology and Security Policy

Bioterorism Resources, Association for Professionals in Infection Control and Epidemiology, Inc.

CDC's Bioterrrorism web site

U.S.Army Medical Research Institute of Infectious Diseases (USARMRIID), Fort Detrick, MD

Health Canada/ Office of Biosafety : Bioterrorism Statement

Bioterrorism Readiness Plan - A Template for Health Care Facilities, APIC

Bioterrorism and Public Health Summary (Health Canada)

Biological and Chemical Terrorism: Strategic Plan for Preparedness and Response. Recommendations of the CDC Strategic Planning Workgroup. MMWR 49 (RR04):1-14. April 21,2000

Chemical and Biological Arms Control Report - Bioterrorism in the United States : The Threat, Preparedness and Response

Center for the Study of Bioterrorism and Emerging Infections (St. Louis University)

Center for Biodefense Studies (John Hopkins University)

Hawley, Robert J., PhD. "Biological Weapons - A Primer for Microbiologists", Annual Review of Microbiology and Human Genetics, 55:235-253. 2001.

Chemical, Biological, Radiological & Nuclear Defense Information Analysis Center

FM3-3 Chemical and Biological Contamination Avoidance, Chapter 4, Biological Agents, U. S. Army

Chemical and Biological Weapons Non-proliferation Project

Federation of American Scientists, Non Proliferation of Weapons of Mass Destruction

Title 32 CFR 627, Subpart H.200, DA Pamphlet 385-69. The Biological Defense Program. Technical Safety Requirements

Medscape - Bioterrorism: Preparing for the Future (Accessible from CDC Bioterrorism web site, you must register to access information through Medscape)

National Symposium on Medical and Public Health Response to Bioterrrorism, Emerging Infectious Diseases, Volume 5, No. 4, July - August 1999

NATO Handbook on the Medical Aspects of Defensive Operations AmedP-6(B), Part II -Biological

Investigating Disease Outbreaks under a Protocol to the Biological and Toxin Weapons Convention Mark Wheelis, University of California, Davis, California USA . Emerging Infectious Diseases 6 (6) 2000 CDC


State Bioterrorism Bills/Laws/Regulations

North Carolina Bioterrorism Agent Registry


Technical Links & Papers

NIH Genetic Modification Clinical Research Information System (GeMCRIS)

American Conference of Governmental Industrial Hygienists (ACGIH)

American Industrial Hygiene Association (AIHA)

From the CDC web site: CDC Hospital Infection Programs

January 17, 1997 CDC Needle Safety Device Study

RTECS - Registry of Toxic Effects of Chemical Substances

The BMBL is available directly from:

CDC Prevention Guidelines Database

Consolidated CDC Post- Exposure Recommendations (June 29,2001)

DHHS/PHS National Toxicology Program, 10th Report on Carcinogens

From the OSHA web site: Latex Allergy folder

Needlestick Prevention Folder, including the revised OSHA bloodborne pathogen compliance directive

The above OSHA needlestick folder includes links to the following sites: University of Virginia Health Care Worker Safety Center

Emergency Care Research Institute

Training for Development of Innovative Control Technologies

California SHARPS Program


More technical web links

Occupational & Environmental Medicine

National Pesticide Information Center

Canadian Pathogen Safety Data Sheets (PSDS)

American Type Culture Collection

Virus Databases on Line

Journal of Gene Medicine

Knowing How to Practice Safe Science (Howard Hughes Institute)

OIE - World Organization for Animal Health


More CDC articles

Update: Investigation of Anthrax Associated with Intentional Exposure and Interim Public Health Guidelines, October, 2001

Recognition of Illness Associated with the Intentional Release of a Biologic Agent

Investigation of case of anthrax in Texas Laboratory Worker

Investigation of case of anthrax in Texas Laboratory Worker

State of Alaska Department of Human Services : Bugwars (Community Tabletop Bioterrorism Exercise)

ASHRAE Report: "Risk Management Guidance for Health and Safety Under Extraordinary Circumstances" - January 12, 2002 (PDF. file, under "News and Events")

Lawrence Berkley National Laboratory

CDC/NIH: Guidance for Protecting Building Environments from Airborne Chemical, Biological and Radiological Attacks

Office of Homeland Security

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